UC CORE

UC CORE
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  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III
  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III
Home Labs Target Nomination Target Validation Statistics and Data Mining

Statistics and Data Mining

The use of statistics and data mining such as image recognition and other advanced modalities to assess statistical significance and data quality for the purpose of target validation and quantification of phenotypes.

UCLA Molecular Screening Shared Resource (MSSR)

The Molecular Screening Shared Resource (MSSR) offers high throughput screening (HTS) services for drug discovery, chemical and functional genomics. Supported are all readouts including high …

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UCLA Semel Institute Biostatistics Core (SIStat)

The Semel Institute Biostatistics Core (SIStat) is a team of expert biostatisticians, methodologists and research support staff. The mission of the Core is to foster …

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UCLA Department of Medicine Statistics Core (DOMStat)

The primary objective of DOMStat is to provide state-of-the-art study design and statistical analysis collaboration to investigators in the Department of Medicine as well as …

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UCLA Informatics Center for Neurogenetics and Neurogenomics (ICNN)

As with other areas of biomedical science, the post-genome era raises the prospect of transformational advances in neuroscience research. Neuroscience faces special challenges, however, in …

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UCLA Statistical/Biomathematical Consulting Clinic

Provides consulting including grant preparation and timely help to researchers in the health sciences and other areas. Experineced in a wide range of applications, including …

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