UC CORE

UC CORE
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  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III
  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III
Home Labs Lead Optimization ADME CYP Panel: Inhibition, Induction

CYP Panel: Inhibition, Induction

CYPs are cytochrome P450 Proteins. A CYP panel assesses genetic risk of drug metabolism for drugs metabolized by these enzymes. This aids in drug selection and dose planning.

UCLA Molecular Screening Shared Resource (MSSR)

The Molecular Screening Shared Resource (MSSR) offers high throughput screening (HTS) services for drug discovery, chemical and functional genomics. Supported are all readouts including high …

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UCSD Clinical Pharmacology and Assay Laboratory

Provides quantitative assays of pharmaceutical agents and biochemical markers. Core equipment includes 3 Beckman HPLCs and 2 API 4000 LC-MS/MS Systems Main Contact: Dr. Jeremiah …

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