This facility provides comprehensive proteomics services using mass spectrometry, determining the protein contents of samples as simple as gel bands or as complicated as whole cell extracts. The facility provides identification of posttranslational modifications and relative quantitation as well as consultation regarding sample preparation and experimental design.

The UCB Proteomics/Mass Spectrometry Laboratory (P/MSL) was founded in 2004 as part of UCB’s Cancer Research Laboratory.  In 2007, they became the Vincent J. Coates Proteomics Laboratory, affiliated with QB3, in order to provide improved access to Proteomics services. Now they occupy a spacious laboratory in Stanley Hall with a “wet” biochemistry area for protein sample preparation and room for expansion of their array of mass spectrometers.

The P/MSL provides proteomics services principally through mass spectrometry.  Currently, they have two Thermo LTQ XL linear ion trap mass spectrometers and a Thermo Fusion Lumos mass spectrometer.

They specialize in the identification of proteins from complex samples using MudPIT chromatography as developed in the Yates lab. They can locate post-translational modifications, often even on complex samples. Now they offer high resolution analysis for isobaric or SILAC relative quantitation. Many other types of analysis are possible.

To learn how you can work with Vincent J. Coates Proteomics/Mass Spectrometry Laboratory please visit their webpage here. Specific services and rates can be found here.