UC CORE

UC CORE
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  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III
  • Target Nomination
    • Target Identification
      • Proteomics
      • Bioinformatics
      • Functional Genomics
      • Assay Development
      • Deep Sequencing
    • Target Validation
      • Functional Genomics
      • Proteomics
      • Assay Development
      • Compound Synthesis
      • Statistics and Data Mining
  • Hit Generation
    • Compound Screening
      • High Throughput Screening (HTS)
      • High Content Screening
      • Data Mining of Screening Data
      • Computational Chemistry and Structural Biology
      • Fragment Based Screening
      • Compound Libraries
    • Hit Triage
      • Potency Determination
      • Purity Determination by LC-MS
      • Small Molecule NMR
      • Similarity Analysis
  • Lead Optimization
    • Chemical
      • Compound Synthesis
      • Cheminformatics
    • Cellular and Molecular Pharmacology
      • Binding Affinity
      • Cellular Disease Models
      • Potency Determination
      • Selectivity Profiling
    • Drug Mode of Action Determination
      • Functional Genomics
      • Next Gen Sequencing
    • Cytotoxicity
      • Hepatotoxicity
      • Genotoxicity
      • Mitochondria Toxicity
    • Activity Testing
      • Potency Determination
      • Selectivity Profiling
    • Structural Biology
      • Crystallography, NMR – BioMolecule
      • Crystallography, NMR – Small Molecule
    • ADME
      • In Vitro Triage Studies
      • CYP Panel: Inhibition, Induction
      • In Vivo Pharmacokinatics (PK)
    • PK and PD Method Development
    • Toxicology
      • Mouse Toxicology: 7 and 21 day
      • Mouse Toxicology: Dose Finding
      • Blood Chemistry
    • Biomarkers
      • Assay Development
      • Proteomics
    • Efficacy Testing
      • In Vitro
      • In Vivo
  • Preclinical Development
    • Non-GLP Safety Testing
      • Mouse Toxicology
      • 7 and 21 Day Studies
      • Dose Range Study
    • GLP Safety Testing (IND Enabled)
      • Biomarker Development
      • Mouse Toxicology
      • ADME
      • Initial Rodent pharmacokinetics (PK)
      • Pharmacodynamics (PD) Assay Development
    • Synthesis and Manufacturing
  • Clinical Development
    • Document Preparation
    • Phase I
    • Phase II
    • Phase III

Mouse Toxicology

a preclinical study performed in mouse constructs under GLP to determine the toxicological effects following a dose of the substance of interest.

UCLA Pasarow Mass Spectrometry Laboratory

The UCLA Pasarow Mass Spectrometry Laboratory is an intellectually vibrant group dedicated to the advancement of the science and training of students through innovative research …

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