The mission of the UCLA X-ray Crystallography Core Facility is to provide state-of-the-art resources to researchers at UCLA., enabling the detailed 3-D analysis of biological macromolecules that play essential roles in human health. The facility operates as a full service core that not only offers access to sophisticated equipment and technologies, but also offers advice and technical assitance in sample preparation, data collection, processing, atomic refinement and modeling.

The purpose of the X-ray Crystallography Core Facility is to provide equipment, training, assistance, and technological innovation for determining 3D atomic structures of proteins and other macromolecules.

The X-ray Facility conducts original research in developing and improving crystallographic tools, and helps scientists determine atomic structures. Each structure determined using the Facility not only yields insight into biochemical pathways, but also expands databases used for improving algorithms for fold assignment, structure verification, atomic refinement, potential energy functions, and analysis of protein-protein interactions.

Core Lab Website:
http://www.doe-mbi.ucla.edu/x-ray-crystallography-core-technology-center/

Todd Yeates
yeates@mbi.ucla.edu

Dulio Cascio
cascio@mbi.ucla.edu