The Laboratory for Fluorescence Dynamics (LFD) is a national research resource center for biomedical fluorescence spectroscopy, supported by the National Center for Research Resources (NCRR, 5P41RR003155) and the National Institute of General Medical Sciences (NIGMS, 8P41GM103540) divisions of the National Institutes of Health (NIH) and the University of California, Irvine (UCI). The founder and Principal Investigator of the LFD is Enrico Gratton. The Co-Investigator is Michelle Digman.
The BLI mission is to serve as the world's leading interdisciplinary center for Biomedical Optics by:
• Developing new, enabling biophotonic technologies
• Applying biophotonic technologies to important problems in biology and medicine
• Training students, fellows, and physicians in Biomedical Optics research
• Providing patients with access to advanced therapeutic and diagnostic clinical procedures using biophotonic medical devices
The Beckman Laser Institute (BLI) is a 37,000 square foot multi-disciplinary center for research, teaching, clinical medicine, and technology transfer located on the campus of the University of California, Irvine. The BLI is a division in the Department of Surgery in the School of Medicine and an important unit in the Department of Biomedical Engineering in the School of Engineering.
The In-Vivo Functional Onco-Imaging (IVFOI) shared resource supports basic and clinical cancer researchers by providing them with the necessary expertise, imaging instrumentation, and image analysis techniques.
The UC Irvine Experimental Tissue Resource (ETR) provides four major types of service (outlined below). The ETR is a Shared Resource funded in part by the Chao Family NCI-Comprehensive Cancer Center Support Grant (P30CA062203) from the National Cancer Institute, and has facilities both on the UC Irvine campus as well as at the UC Irvine Medical Center. ETR services are available to both on- and off-campus investigators.
Tissue Procurement and Interpretive Histopathology Consultation
The Transgenic Mouse Facility (TMF) facilitates the use of genetically modi¬fied mice in biological and biomedical research. An important goal of the TMF is to identify new technology and methodology that is likely to benefi¬t UC Irvine investigators using the mouse in their research programs and to import and provide such technology to UC Irvine investigators. The TMF makes investigators aware of new and existing developments via the TMF website, in seminars and lectures, via the UC Irvine MouseUsers email list and by word of mouth.
The West Coast Metabolomics Center (WCMC), located at the University of California, is at the forefront of metabolomic innovation and service. We help researchers at UC Davis and extramural scientists with services, training and collaborative activities in biological and biomedical projects.
"The Crump Institute's Preclinical Imaging Technology Center, located on the main campus of UCLA in the California NanoSystems Institute, advances state-of-the-art small animal imaging. It functions both as a shared preclinical imaging resource for UCLA researchers and as a hub for emerging imaging research and technology development. The same technologies and services are also available to the larger research community including other academic institutes and industry groups through contract work.
Has a comprehensive collection of instrumentation for macro-scale molecular imaging using fluorescence, near-infrared, life-time and time-gated imaging modalities.
The Immune Assessment Core is a comprehensive source of immune assessment testing services for basic, clinical and translational studies. The full service laboratory performs various immunological assays to evaluate the innate and adaptive immune status of study subjects.
The Immune Assessment Core focuses on developing assays using cutting edge, high throughput technologies. We obtain the highest quality data to survey the immune system using small sample volumes. This is achieved by providing validated assays with multiplexed capacities. We work closely with our clients to assist with analysis and interpretation of the comprehensive data sets to ensure they get the most out of the samples they have collected. In addition to the above mentioned assays, the core performs customized assay development to meet the client's developing needs.
The Mouse Physiology Laboratory is dedicated to the phenotypic assessment of mouse and rat models of disease using a wide variety of integrative approaches. Our aim is to provide a cost effective means for investigators to reveal important functional aspects of their mouse and rat models without having to individually invest in hiring skilled personnel and in the purchase of expensive instrumentation. We will work with you to design and implement the study along with any associated grant, animal protocol and manuscript preparation. The laboratory has collaborated with dozens of investigators at UCLA and other institutions worldwide on a wide range of studies leading to numerous peer reviewed publications.