The UCSF Preclinical Therapeutics Core (PTC) facility generates tumor-bearing animals and conducts preclinical oncology trials for UCSF Helen Diller Family Comprehensive Cancer Center investigators. Offering a variety of xenograft and allograft-based cancer models, the core provides a complete set of services that include consultation regarding experimental design, tumor cell growth in culture, generation of tumors in mice, formulation and administration of experimental agents, monitoring of tumor burden and response to therapy, and preparation and interpretation of study results.
The Center for Advanced Technology (CAT) is a part of the Department of Biochemistry and Biophysics at the University of California, San Francisco. Our primary mission is to support research labs at UCSF through the resources that we host, but other academic and biotechnology organizations are welcome to use our facility through prior arrangements.
For over 21 years, the UCSF/CFAR Core Immunology Lab (CIL) has been dedicated to providing immunology assays, expert consultation, and education to the UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.
The SMDC collaborates with academics, government labs, and pharma companies to develop unique chemical probes and drug leads, using high-throughput screening, high-content imaging, fragment discovery, and medicinal chemistry. Data is accessed via the web using a home-build platform called HiTS.
Core Lab Website:
The Parnassus Flow Cytometry Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as the isolation of cells based on those markers. Advanced cell sorting and cytometric analyses are readily conducted by experts within the Core or by trained laboratory members.
The Laboratory for Fluorescence Dynamics (LFD) is a national research resource center for biomedical fluorescence spectroscopy, supported by the National Center for Research Resources (NCRR, 5P41RR003155) and the National Institute of General Medical Sciences (NIGMS, 8P41GM103540) divisions of the National Institutes of Health (NIH) and the University of California, Irvine (UCI). The founder and Principal Investigator of the LFD is Enrico Gratton. The Co-Investigator is Michelle Digman.
The BLI mission is to serve as the world's leading interdisciplinary center for Biomedical Optics by:
• Developing new, enabling biophotonic technologies
• Applying biophotonic technologies to important problems in biology and medicine
• Training students, fellows, and physicians in Biomedical Optics research
• Providing patients with access to advanced therapeutic and diagnostic clinical procedures using biophotonic medical devices
The Beckman Laser Institute (BLI) is a 37,000 square foot multi-disciplinary center for research, teaching, clinical medicine, and technology transfer located on the campus of the University of California, Irvine. The BLI is a division in the Department of Surgery in the School of Medicine and an important unit in the Department of Biomedical Engineering in the School of Engineering.
The In-Vivo Functional Onco-Imaging (IVFOI) shared resource supports basic and clinical cancer researchers by providing them with the necessary expertise, imaging instrumentation, and image analysis techniques.
The UC Irvine Experimental Tissue Resource (ETR) provides four major types of service (outlined below). The ETR is a Shared Resource funded in part by the Chao Family NCI-Comprehensive Cancer Center Support Grant (P30CA062203) from the National Cancer Institute, and has facilities both on the UC Irvine campus as well as at the UC Irvine Medical Center. ETR services are available to both on- and off-campus investigators.
Tissue Procurement and Interpretive Histopathology Consultation
The Transgenic Mouse Facility (TMF) facilitates the use of genetically modi¬fied mice in biological and biomedical research. An important goal of the TMF is to identify new technology and methodology that is likely to benefi¬t UC Irvine investigators using the mouse in their research programs and to import and provide such technology to UC Irvine investigators. The TMF makes investigators aware of new and existing developments via the TMF website, in seminars and lectures, via the UC Irvine MouseUsers email list and by word of mouth.