The UCSF NMR Lab provides a range of state-of-the-art NMR facilities that are available for use by qualified academic and outside researchers. Besides experiments to identify and determine the structure of small organic molecules, the high-field NMR spectrometers (ranging from 400 to 800 MHz for 1H NMR) are capable of protein and RNA structure determination. This is accomplished via heteronuclear (e.g., 1H, 13C, 15N, 31P) multi-dimensional NMR spectra, often using locally written and widely distributed software (e.g., Sparky, MARDIGRAS, CORMA) for data analysis.
The SMDC collaborates with academics, government labs, and pharma companies to develop unique chemical probes and drug leads, using high-throughput screening, high-content imaging, fragment discovery, and medicinal chemistry. Data is accessed via the web using a home-build platform called HiTS.
Core Lab Website: