Labs

  • Featuring an 800 MHz NMR, EPR and Biacore SPR The 800 MHz NMR spectrometer (1394 Natural Sciences I) can detect proton, carbon and nitrogen signals and is equipped with hardware optimized for biomolecular applications. The Biacore 300 instrument (1304 Natural Sciences I) can measure docking interactions and binding affinity between biomolecules.
    http://www.research.uci.edu/facilities-services/shared-facilities/index....

  • Established in 2015, IMRI was built on the previous Laboratory for Electron and X-ray Instrumentation (LEXI) and newly established transmission electron microscopy (TEM) facilities. Today, IMRI operates a large number of open-access user facilities for the characterization of inorganic, organic, and biological materials and devices ranging from sub-Å to macroscopic length scales - available to all university, industry, and non-profit researchers.

  • The Optical Biology Core (OBC) operates under the theme that technology enables discovery. Consequently, the goal of the OBC is to provide the best conventional microscopy platforms available and to develop and introduce novel optical methods that allow new discoveries to be made.

  • The facility incorporates a variety of pulsed and continuous wave laser systems. In general, our pulsed laser systems are tunable through the use of optical parametric oscillators. We also operate and maintain tools for Raman microscopy and conventional linear and non-linear spectroscopy applications. We offer assistance in data acquisition, analysis and discussion. Consultation services spanning the wide range of disciplines including linear and nonlinear spectroscopy, ultrafast phenomena and light-matter interactions. Circular Dichroism is also available in this facility.

  • The Laser Microbeam and Medical Program (LAMMP), is dedicated to the use of lasers and optics in Biology and Medicine. LAMMP is located within the Beckman Laser Institute and Medical Clinic, an interdisciplinary biomedical research, teaching, and clinical facility at the University of California, Irvine. LAMMP activities span from basic science and technology development to clinical translational research.

  • The Biostatistics Shared Resource (BSR) supports the conception, design, implementation, analysis and reporting of research conducted by members of the Chao Family Comprehensive Cancer Center. In addition, BSR faculty serve as liaisons to each of the cancer center’s Disease-Oriented Teams, keeping abreast of team developments and providing a first point of contact for assistance from the BSR with study design, data analysis, and new grant development.
    Need statistical help?

  • The UCSD Screening Core provides infrastructure and consulting expertise for the development and implementation of screening assays in small, medium and high-throughput scale.

  • The Molecular Screening Shared Resource (MSSR) offers a comprehensive range of leading-edge high throughput screening (HTS) services including drug discovery, chemical and functional genomics, and novel methods for nano and environmental toxicology. The MSSR is an open access environment with investigators from UCLA as well as from the entire globe. Industrial clients are equally welcome as are non-profit entities.

  • The UCLA Crystallization Facility provides state-of-the-art, high-throughput, crystallization services to all institutions. The full-service core offers access to sophisticated equipment and technologies, and technical assistance in sample preparation. The facility will provide screen preparation, plate setup, automated image acquisition and analysis, and optimization design. Our high-throughput set up can produce 18,000 experiments in a single day.

  • The Mitochondria and Metabolism Core at UCLA provides the scientific community with the necessary technical and conceptual resources for studying mitochondrial function. We provide access to Seahorse XF96 Extracellular Flux Analyzers and an Operetta High Content Imager, which users can schedule after training. Additionally, The Mitochondria Core provides a number of full service options for the design, performance, analysis and interpretation of fundamental mitochondrial assays.

    Orian Shirihai, MD PhD
    oshirihai@mednet.ucla.edu