Labs

  • The UCSF NMR Lab provides a range of state-of-the-art NMR facilities that are available for use by qualified academic and outside researchers. Besides experiments to identify and determine the structure of small organic molecules, the high-field NMR spectrometers (ranging from 400 to 800 MHz for 1H NMR) are capable of protein and RNA structure determination. This is accomplished via heteronuclear (e.g., 1H, 13C, 15N, 31P) multi-dimensional NMR spectra, often using locally written and widely distributed software (e.g., Sparky, MARDIGRAS, CORMA) for data analysis.

  • The Center for Advanced Technology (CAT) is a part of the Department of Biochemistry and Biophysics at the University of California, San Francisco. Our primary mission is to support research labs at UCSF through the resources that we host, but other academic and biotechnology organizations are welcome to use our facility through prior arrangements.

  • For over 21 years, the UCSF/CFAR Core Immunology Lab (CIL) has been dedicated to providing immunology assays, expert consultation, and education to the UCSF and global research community. CIL specializes in developing immunology research tools, and initiating and stimulating innovative research projects to address emerging questions in immunologic diseases including HIV pathogenesis.

  • The SMDC collaborates with academics, government labs, and pharma companies to develop unique chemical probes and drug leads, using high-throughput screening, high-content imaging, fragment discovery, and medicinal chemistry. Data is accessed via the web using a home-build platform called HiTS.

    Michelle Arkin
    michelle.arkin@ucsf.edu

    Core Lab Website:
    http://smdc.ucsf.edu/index.htm

  • The Laboratory for Cell Analysis provides cytometric, microscopic, and genomic support and services for the UCSF Helen Diller Family Comprehensive Cancer Center. The LCA was established in 1983 with the following responsibilities:

  • The Parnassus Flow Cytometry Core assists investigators whose research requires molecular marker characterization of cells in suspension as well as the isolation of cells based on those markers. Advanced cell sorting and cytometric analyses are readily conducted by experts within the Core or by trained laboratory members.

  • Featuring an 800 MHz NMR, EPR and Biacore SPR The 800 MHz NMR spectrometer (1394 Natural Sciences I) can detect proton, carbon and nitrogen signals and is equipped with hardware optimized for biomolecular applications. The Biacore 300 instrument (1304 Natural Sciences I) can measure docking interactions and binding affinity between biomolecules.
    http://www.research.uci.edu/facilities-services/shared-facilities/index....

  • Established in 2015, IMRI was built on the previous Laboratory for Electron and X-ray Instrumentation (LEXI) and newly established transmission electron microscopy (TEM) facilities. Today, IMRI operates a large number of open-access user facilities for the characterization of inorganic, organic, and biological materials and devices ranging from sub-Å to macroscopic length scales - available to all university, industry, and non-profit researchers.

  • The Optical Biology Core (OBC) operates under the theme that technology enables discovery. Consequently, the goal of the OBC is to provide the best conventional microscopy platforms available and to develop and introduce novel optical methods that allow new discoveries to be made.

  • The facility incorporates a variety of pulsed and continuous wave laser systems. In general, our pulsed laser systems are tunable through the use of optical parametric oscillators. We also operate and maintain tools for Raman microscopy and conventional linear and non-linear spectroscopy applications. We offer assistance in data acquisition, analysis and discussion. Consultation services spanning the wide range of disciplines including linear and nonlinear spectroscopy, ultrafast phenomena and light-matter interactions. Circular Dichroism is also available in this facility.