Labs

  • The Optical Biology Core (OBC) operates under the theme that technology enables discovery. Consequently, the goal of the OBC is to provide the best conventional microscopy platforms available and to develop and introduce novel optical methods that allow new discoveries to be made.

  • The facility incorporates a variety of pulsed and continuous wave laser systems. In general, our pulsed laser systems are tunable through the use of optical parametric oscillators. We also operate and maintain tools for Raman microscopy and conventional linear and non-linear spectroscopy applications. We offer assistance in data acquisition, analysis and discussion. Consultation services spanning the wide range of disciplines including linear and nonlinear spectroscopy, ultrafast phenomena and light-matter interactions. Circular Dichroism is also available in this facility.

  • The Laboratory for Fluorescence Dynamics (LFD) is a national research resource center for biomedical fluorescence spectroscopy, supported by the National Center for Research Resources (NCRR, 5P41RR003155) and the National Institute of General Medical Sciences (NIGMS, 8P41GM103540) divisions of the National Institutes of Health (NIH) and the University of California, Irvine (UCI). The founder and Principal Investigator of the LFD is Enrico Gratton. The Co-Investigator is Michelle Digman.

  • The Laser Microbeam and Medical Program (LAMMP), is dedicated to the use of lasers and optics in Biology and Medicine. LAMMP is located within the Beckman Laser Institute and Medical Clinic, an interdisciplinary biomedical research, teaching, and clinical facility at the University of California, Irvine. LAMMP activities span from basic science and technology development to clinical translational research.

  • The Transgenic Mouse Facility (TMF) facilitates the use of genetically modiĀ¬fied mice in biological and biomedical research. An important goal of the TMF is to identify new technology and methodology that is likely to benefiĀ¬t UC Irvine investigators using the mouse in their research programs and to import and provide such technology to UC Irvine investigators. The TMF makes investigators aware of new and existing developments via the TMF website, in seminars and lectures, via the UC Irvine MouseUsers email list and by word of mouth.

  • The UCSD Screening Core provides infrastructure and consulting expertise for the development and implementation of screening assays in small, medium and high-throughput scale.

  • The Molecular Screening Shared Resource (MSSR) offers a comprehensive range of leading-edge high throughput screening (HTS) services including drug discovery, chemical and functional genomics, and novel methods for nano and environmental toxicology. The MSSR is an open access environment with investigators from UCLA as well as from the entire globe. Industrial clients are equally welcome as are non-profit entities.

  • Provides testing services, blood and blood cell products and other specialized services to research labs working with HIV and related viruses.

  • The Mitochondria and Metabolism Core at UCLA provides the scientific community with the necessary technical and conceptual resources for studying mitochondrial function. We provide access to Seahorse XF96 Extracellular Flux Analyzers and an Operetta High Content Imager, which users can schedule after training. Additionally, The Mitochondria Core provides a number of full service options for the design, performance, analysis and interpretation of fundamental mitochondrial assays.

    Orian Shirihai, MD PhD
    oshirihai@mednet.ucla.edu